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UGANDA: Striving to provide first-, second- and third-line ARVs

Life-prolonging antiretroviral (ARV) medication is reaching more HIV-positive Ugandans than ever before, but health workers are concerned about how they will deal with the inevitable rise in drug resistance.

Published
01 December 2010
From
IRIN Plus News
All HIV patients to get second-line treatment free

All HIV patients put on antiretroviral therapy before 2004 but who became resistant to those drugs will now receive the life saving second line treatment free of cost from the National AIDS Control Organisation (NACO).

Published
13 November 2010
From
Times of India
Darunavir working well for highly treatment-experienced patients in Switzerland

Outcomes for treatment-experienced patients receiving 'salvage therapy' that includes the protease inhibitor darunavir (Prezista) are equal to, or even better, than those seen in clinical trials,

Published
25 October 2010
By
Michael Carter
Darunavir/ritonavir as effective in women as men

Darunavir/ritonavir-based antiretroviral therapy is equally effective in treatment-experienced women and men, US investigators report in the Annals of Internal Medicine. However, within four weeks of the study starting,

Published
22 September 2010
By
Michael Carter
Protease inhibitor to raltegravir switch maintains viral suppression, but NRTI resistance lowers efficacy

People who switched from a suppressive boosted protease inhibitor to the integrase inhibitor raltegravir (Isentress) generally maintained undetectable viral load with improvements in blood lipid levels, according

Published
22 July 2010
By
Liz Highleyman
Once-daily Kaletra approved for some treatment-experienced adults

Drug regulatory authorities in the US have approved once-daily dosing of Kaletra for some treatment experienced-patients. The Food and Drug Administration (FDA) announced on April

Published
29 April 2010
By
Michael Carter
Protease inhibitor monotherapy in clinical practice: valid option for undetectable patients

Patients prescribed protease inhibitor-ritonavir (PI/r) monotherapy in ‘real-world’ clinical practice achieve viral suppression rates equivalent to those seen in randomised controlled trials, according to two

Published
27 April 2010
By
Gus Cairns
Resistance tests useful for patients with very low viral loads

Genotypic tests are able to detect resistance to antiretroviral drugs in patients with low viral load, UK research published in the May 1st edition of

Published
08 April 2010
By
Michael Carter
Darunavir/ritonavir, etravirine and raltegravir combination has 'remarkable' success in children with resistant virus

A combination of darunavir/ritonavir, etravirine, and raltegravir is “remarkably” effective in HIV-positive adolescents with extensive prior experience of antiretroviral therapy, French investigators report in the

Published
30 October 2009
By
Michael Carter
Etravirine, darunavir/ritonavir and raltegravir very effective in highly treatment-experienced patients

A combination of raltegravir, etravirine and darunavir/ritonavir is highly effective at suppressing viral load to undetectable levels in treatment-experienced patients, French investigators report in the

Published
19 October 2009
By
Michael Carter

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